FINNENCE ▪ THE WIRE FILE
THE WIRE · № 67712
Company▼ Bearish
Phase 3 results posted: A Study of Aticaprant in Adult and Elderly Participants With Major Depressive Disorder (MDD) — Janssen Research & Development, LLC
KINDCompany
DIRECTION▼ Bearish
SOURCES1
ENTITIES2
STORY SIZESTANDALONE
FIRST SEEN2026-10-06 12:00 UTC
LAST UPDATE2026-10-06 12:00 UTC
STATEactive
01 THE MACHINE READ
WHY IT MATTERS.
A terminated Phase 3 depression trial removes a potential pipeline asset and signals efficacy or safety problems.
Terminated depression trial weakens pipeline outlook
CATALYST TO WATCH
Disclosure of termination reasons
MAIN RISK
Further pipeline attrition in CNS
FULL DISPATCH
Sponsor: Janssen Research & Development, LLC; Status: Terminated; Conditions: Depressive Disorder, Major; Interventions: Aticaprant; Enrollment: 871 (actual); First posted: 2022-08-26; Results posted: 2026-10-06; NCT: NCT05518149
02 THE STORY SO FAR
THE RECORD, IN ORDER.
STANDALONE ITEM — NOT YET FOLDED INTO A DEVELOPING STORY.
03 WHO'S INVOLVED
ENTITIES ON FILE.
AFFECTEDJohnson & Johnson · JNJ
AFFECTEDHealthcare
04 RECEIPTS
THE SOURCE RECORD.
1 SOURCES CONFIRMED05 PROPAGATION
WHAT THIS TOUCHES.
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Summaries are generated and may contain errors — every claim links its sources.