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News · ■ Unclear/unknown · 1 source confirmed · 2026-09-29 11:30 UTC

Decoy Therapeutics Reports Preclinical Data Supporting Once-Weekly Intranasal Dosing for DCOY-CoV Program

Why now

Thesis: Early preclinical antiviral data, unproven in humans

Catalyst to watch: IND filing or clinical trial start

Main risk: Preclinical results often fail in humans

Why it matters

Preclinical PK data for an intranasal coronavirus program is early-stage and not yet clinically validated.

Details

Once-Weekly Intranasal Potential: Preclinical PK data demonstrate single-dose drug levels sustained above designed therapeutic concentrations for up to 7 days in nasal mucosal and lung tissue. Addressing Endemic Coronaviruses: DCOY-CoV is designed to protect against endemic human...

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