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News · ■ Unclear/unknown · 1 source confirmed · 2026-09-23 23:30 UTC

Astellas Doses First Patient in Phase 3 Study of setidegrasib in Previously Treated KRAS G12D-Mutated Advanced Non-Small Cell Lung Cancer

Why now

Thesis: Pipeline milestone, no near-term financial impact

Catalyst to watch: Interim trial data or regulatory news

Main risk: Trial failure or delayed readouts

Why it matters

An early Phase 3 start for a KRAS G12D degrader signals pipeline progress but no efficacy or revenue data yet.

Details

- Study evaluates novel, investigational KRAS G12D-targeted protein degrader setidegrasib versus docetaxel in previously treated patients with advanced NSCLC - - Milestone marks second Phase 3 study of setidegrasib initiated within six months - TOKYO, Sept. 23, 2026 /PRNewswire/ --...

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