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News · ■ Unclear/unknown · 1 source confirmed · 2026-09-23 13:46 UTC

New model-based analysis further supports the potential of TECVAYLI® (teclistamab-cqyv) plus DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj) to redefine long-term survival expectations in early line relapsed/refractory multiple myeloma

Why now

Thesis: Supports earlier-line myeloma positioning for J&J combo

Catalyst to watch: Regulatory review or trial readouts for earlier lines

Main risk: Model-based analysis may not replicate in trials

Why it matters

Survival analyses for teclistamab plus daratumumab could support earlier-line use, but model-based analyses are not new trial data.

Details

Analysis shows ~87% of patients treated with TECVAYLI® plus DARZALEX FASPRO® as early as second line were estimated to have comparable mortality risk to the general population A separate analysis shows the survival benefit was driven by a 90% reduction in the risk of multiple myeloma...

Related assets & topics

Johnson & Johnson · JNJHealthcare

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